β-Catenin: Friend or Foe in Heart Disease PANoptosis Unveiled in Cardiomyopathy Gene Deletion Reveals Causes of Cardiomyopathy WNT Pathway: Master Controller of Cell Life Overview My cardiovascular research explores the molecular mechanisms underlying cardiomyopathies, with a specific focus on genetic factors such as β-catenin and desmoplakin. I have investigated the roles of these molecules in cell cycle regulation, mitochondrial function, and cell death processes, like PANoptosis, in the heart. This research is directed toward identifying therapeutic targets and strategies to treat or prevent heart failure and other relevant conditions.

Nature’s Shield Against Inflammation Microglial Inflammation’s New Adversary Powerhouse Protector Against Inflammatory Diseases Natural Inhibitors of Harmful Inflammation Overview My research in inflammation is centered on the mechanisms of inflammasome activation, particularly the NLRP3 inflammasome, and its role in chronic diseases such as multiple sclerosis and Alzheimer’s disease. I have examined how various compounds, including phytochemicals and sulforaphane, modulate inflammatory pathways and prevent disease progression. This work aims to uncover novel anti-inflammatory strategies that can be applied to both neurodegenerative and systemic diseases.

Microglia Ramp Up Defense in Alzheimer’s Brains Neuronal Vesicles Hold Clues in Alzheimer’s Novel Exosomal Biomarkers Uncovered Melatonin: Combating Depression and Brain Inflammation Overview My studies in neuroscience focus on understanding the cellular and molecular mechanisms underlying neurodegenerative diseases, such as Alzheimer’s disease, with a particular emphasis on the role of microglia and exosomalsignaling. I have explored the impact of inflammatory pathways and the microenvironment on neuronal health, aiming to identify biomarkers and therapeutic targets. Additionally, I’ve investigated the effects of external stimuli, such as mechanical forces, on neuron function and survival, contributing to our knowledge of neuroprotection and neurodegeneration.